In locally advanced breast cancer

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Breast Disease pp Cite as. Patients with locally advanced breast cancer LABC have historically been considered inoperable cases. However, in light of recent research and studies, even metastatic breast cancers have been down-staged to operable cases using new treatment modalities. Annually, ,—, new cases of LABC are diagnosed worldwide. According to the American Joint Committee on Cancer AJCC staging system, LABC is classified as follows: T3, large tumors; T4, tumors with skin or chest wall involvement; N2, nodal disease with fixed or matted axillary lymph nodes; and N3, nodal disease with involvement of the ipsilateral subclavicular and supraclavicular lymph nodes [4].
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About advanced cancer

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What is Advanced, Metastatic and Stage 3 & 4 Breast Cancer?

Click on image for details. The advancement of disease leads to decreased probability of radical cure and increase in treatment cost. The study evaluated neo adjuvant chemotherapy with MRM and MRM followed by adjuvant chemotherapy and also the effectiveness of neo-adjuvant chemotherapy in down staging advanced disease and offering radical cure. Settings And Design: A rural hospital-based prospective comparative study.
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Surgical Management of Locally Advanced Breast Cancer

Submit Manuscript. Journal Home. Editorial Board. Submit to this journal. Special Issues.
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If you or a loved one has been diagnosed with advanced or metastatic breast cancer, understanding the disease is a first step to finding the best treatment option. Use these resources to learn about the different types of breast cancer, the treatment options available, and how to get the most of the time with the doctor. Breast cancer begins when abnormal cancerous cells in the breast grow and multiply without stopping, creating a tumor.

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